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==HRA Pharma==
HRA Pharma is a global independent pharmaceutical company dedicated to niche areas of women’s health[1] and endocrinology[2]. Headquartered in Paris, France HRA Pharma has direct local operations in 9 European countries (Belgium, France, Germany, Ireland, Italy, Portugal, Spain, Switzerland, the United Kingdom) and a broad network of distribution partners worldwide. The company’s products are registered and sold in more than 80 countries worldwide. HRA Pharma employs 130 people globally (as of Sept 2014). In 2013, the company’s revenue was €60 million.[3]
===History=== HRA Pharma began in 1996 as a development project by André Ulmann, physician and former Medical Director and Head of Clinical Research for Roussel-Uclaf and Hoechst-Marion-Roussel. André Ulmann identified women’s reproductive health as an important and poorly addressed field and focused on emergency contraception[4], an area with a significant unmet medical need. [5] HRA Pharma was incorporated as a privately held company in 1998. Its mission statement from the outset was to “develop and market medicines that respond to a clear-cut medical need but do not trigger interest from large pharmaceutical companies”.During the first few years of business, Dr. Ulmann built up a small team of professionals in Paris that pioneered HRA Pharma’s first product, NorLevo (levonorgestrel[6]) – an emergency contraceptive pill. Launched in France in 1999[7], it was approved for marketing throughout Europe one year later[8][9][10][11]. Given the interest generated by this product from a public health perspective, the French authorities enacted policies to make it widely accessible to patients[12]. As a result, it became the first hormonal contraceptive product to be made available without prescription[13], and the first to be made available free of charge to under 18 year olds[14]. NorLevo® is now available in over 50 countries worldwide[15]. The success of Norlevo enabled the company to expand its women’s health franchise, and led to the development of another compound - ulipristal acetate[16], a proprietary first-in-class selective progesterone receptor modulator. Following a complete development program, ulipristal acetate was approved for use as emergency contraception in 2009[17] and is currently marketed under the trade name ellaOne or ella (30 mg tablet) in over 60 countries. Ulipristal acetate is also available in a different strength and different dosage regimen as Esmya®, a treatment for uterine fibroids[18]. In 2014, the company launched Clareva, a symptomatic treatment of genital herpes[19]. In parallel to the development of its women’s health franchise, the company expanded into the field of rare endocrine diseases and diversified its portfolio through organic growth, partnerships and acquisitions. In the field of rare endocrine diseases, the company’s markets treatments for rare, severe diseases including Cushing’s syndrome[20] and adrenal cortical cancer[21]. HRA Pharma endocrine brands include Ketoconazole HRA (ketoconazole[22]), Lysodren (mitotane[23]) and Metopirone (metyrapone[24]). The company is a specialist in niche areas of women’s health and endocrinology.
===Key products===
Women’s health • Clareva (oxidised triglycerides) • ellaOne (ulipristal acetate[25]) • esmya (ulipristal acetate[26]) • NorLevo (levonorgestrel[27])
Endocrinology • Ketoconazole HRA (ketoconazole[28]) • Lysodren (mitotane[29]) • Metopirone (metyrapone[30])
===Corporate governance===
Erin Gainer has been HRA Pharma's Chief Executive Officer since 2009. André Ulmann is the Founder of HRA Pharma and Chairman of its Board of Directors, a position he has held since 2009[31].
- https://en.wikipedia.org/wiki/Women%27s_health
- https://en.wikipedia.org/wiki/Endocrinology
- www.hra-pharma.com
- https://en.wikipedia.org/wiki/Emergency_contraception
- "Créer une entreprise pharmaceutique sans capital" http://ecole.org/fr/seances/SEM127
- https://en.wikipedia.org/wiki/Levonorgestrel
- http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68196192)
- http://www.legemiddelverket.no/Legemiddelsoek/Sider/default.aspx?searchquery=levonorgestrel&f=Han;MtI;Vir;ATC;Var;Mar;Mid;Avr;&pane=0
- http://www.cbg-meb.nl/CBG/en/human-medicines/geneesmiddeleninformatiebank/default.htm
- http://www.fimea.fi/medicines/fimeaweb
- http://www.fagg-afmps.be/fr/items/banque_donnees/
- Improving access : “the French Experience” https://www.guttmacher.org/pubs/tgr/05/5/gr050510.html)
- http://www.assemblee-nationale.fr/legislatures/11/pdf/rap-info/i2593.pdf
- http://www.legifrance.gouv.fr/affichTexte.do;jsessionid=F91A2E848D9F21C78D134C3879B70A56.tpdjo02v_3?cidTexte=LEGITEXT000005632081&dateTexte=20141120
- Worldwide availability: http://www.hra-pharma.com/index.php/en/our_products/womens_health/emergency_contraception/norlevo)
- https://en.wikipedia.org/wiki/Ulipristal_acetate
- http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/001027/human_med_000758.jsp&mid=WC0b01ac058001d124)
- https://en.wikipedia.org/wiki/Uterine_fibroids
- https://en.wikipedia.org/wiki/Genital_herpes
- https://en.wikipedia.org/wiki/Cushing_syndrome
- https://en.wikipedia.org/wiki/Adenocortical_carcinoma
- https://en.wikipedia.org/wiki/Ketoconazole
- https://en.wikipedia.org/wiki/Mitotane
- https://en.wikipedia.org/wiki/Metyrapone
- https://en.wikipedia.org/wiki/Ulipristal_acetate
- https://en.wikipedia.org/wiki/Ulipristal_acetate
- https://en.wikipedia.org/wiki/Levonorgestrel
- https://en.wikipedia.org/wiki/Ketoconazole
- https://en.wikipedia.org/wiki/Mitotane
- https://en.wikipedia.org/wiki/Metyrapone
- http://www.hra-pharma.com/index.php/fr/notre_entreprise/decouvrir_hra_pharma/notre_gouvernance
www.hra-pharma.com Créer une entreprise pharmaceutique sans capital http://ecole.org/fr/seances/SEM127 http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68196192) http://www.legemiddelverket.no/Legemiddelsoek/Sider/default.aspx?searchquery=levonorgestrel&f=Han;MtI;Vir;ATC;Var;Mar;Mid;Avr;&pane=0 http://www.cbg-meb.nl/CBG/en/human-medicines/geneesmiddeleninformatiebank/default.htm http://www.fimea.fi/medicines/fimeaweb http://www.fagg-afmps.be/fr/items/banque_donnees/ https://www.guttmacher.org/pubs/tgr/05/5/gr050510.html) http://www.assemblee-nationale.fr/legislatures/11/pdf/rap-info/i2593.pdf http://www.legifrance.gouv.fr/affichTexte.do;jsessionid=F91A2E848D9F21C78D134C3879B70A56.tpdjo02v_3?cidTexte=LEGITEXT000005632081&dateTexte=20141120 Worldwide availability: http://www.hra-pharma.com/index.php/en/our_products/womens_health/emergency_contraception/norlevo) https://en.wikipedia.org/wiki/Ulipristal_acetate https://en.wikipedia.org/wiki/Women%27s_health https://en.wikipedia.org/wiki/Endocrinology https://en.wikipedia.org/wiki/Levonorgestrel http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/001027/human_med_000758.jsp&mid=WC0b01ac058001d124) https://en.wikipedia.org/wiki/Uterine_fibroids https://en.wikipedia.org/wiki/Genital_herpes https://en.wikipedia.org/wiki/Cushing_syndrome https://en.wikipedia.org/wiki/Adenocortical_carcinoma https://en.wikipedia.org/wiki/Ketoconazole https://en.wikipedia.org/wiki/Mitotane https://en.wikipedia.org/wiki/Metyrapone http://www.hra-pharma.com/index.php/fr/notre_entreprise/decouvrir_hra_pharma/notre_gouvernance