The file size of this SVG image may be abnormally large because most or all of its text has been converted to paths rather than using the more conventional <text> element. Unless rendering the text of the SVG file produces an image with text that is incurably unreadable due to technical limitations, it is highly recommended to change the paths back to text. Doing so will ease the process of localizing this image to other languages and is likely to reduce the file size in a significant scale. Other SVGs containing path-based text can be found at Category:Path text SVG. For more information, see SVG: Fonts and Preparing images for upload: Text.
Overview of the miRNAs biogenesis. In the canonical pathway in the nucleus, pri-miRNAs are cleaved into pre-miRNAs by Drosha. Pre-miRNAs are exported to the cytoplasm by exportin 5. In the cytoplasm, pre-miRNAs are cleaved into small dsRNAs by Dicer. Then, RISC mediates the recognition of the mRNA to be targeted. In the non-canonical pathway (Mirtron), Drosha cleavage is substituted with splicing. pri-miRNAs (pre-mRNAs) are processed to pre-miRNAs by the spliceosome machinery and debranching enzyme to generate double-stranded loop structures like the regular miRNAs. Subsequently, the RNA product of splicing adopts a pre-miRNA like form, and transferred to the cytoplasm by exportin 5 to continue with the canonical pathway. For more details please refer to the text.
Description
DescriptionMiRNA.svg
English: Diagram of microRNA. Based on [1], [2], [3], the wikipedia article, and various other sources.
The editable text is in this file, off beyond the page boundaries.
de partager – de copier, distribuer et transmettre cette œuvre
d’adapter – de modifier cette œuvre
Sous les conditions suivantes :
paternité – Vous devez donner les informations appropriées concernant l'auteur, fournir un lien vers la licence et indiquer si des modifications ont été faites. Vous pouvez faire cela par tout moyen raisonnable, mais en aucune façon suggérant que l’auteur vous soutient ou approuve l’utilisation que vous en faites.
https://creativecommons.org/licenses/by/3.0CC BY 3.0 Creative Commons Attribution 3.0 truetrue
Légendes
Ajoutez en une ligne la description de ce que représente ce fichier
A schematic showing the formation and function of micro RNA.
A schematic showing the formation and function of micro RNA.